Edges of the Mind
Treating Schizophrenia as Psychiatry Evolves
A powerful memoir from one of America's leading psychiatrists, chronicling four decades on the front lines of serious mental illness and the remarkable transformation of psychiatry.
Coming Fall 2026
“This book is a powerhouse of drama and science and compassion told through the eyes of a doctor on the frontlines of our nation’s struggle with serious mental illness.”
- Tim Shriver
Chairman of Special Olympics and Founder of UNITE
Why This Book Matters
THE PATIENTS
Series of individuals and families living with schizophrenia.
THE SCIENCE
The breakthroughs that were transformed psychiatry from neuroscience.
THE FUTURE
Why mental health care still has a long way to go.
What You'll Discover
Inside the realities of schizophrenia
The evolution of psychiatric medicine
Behind-the-scenes stories from Yale and NIMH
Breakthrough discoveries in neuroscience
The human side of serious mental illness
Lessons for families, clinicians, and policymakers
Who Should Read This Book
MENTAL HEALTH PROFESSIONALS
Psychiatrists, psychologists, counselors, social workers, and technicians.
FAMILIES
Loved ones affected by serious mental illness seeking understanding and hope.
STUDENTS
Medicine, neuroscience, psychology. public health, and related fields.
GENERAL READERS
Anyone interested in medicine, science, and stories of resilience and discovery.
Why I Wrote Edges of the Mind
Each time I sat with a patient living with schizophrenia and tried to understand the often-painful reality of their illness, I felt a strong need to write about what I had witnessed. I did not want to write another scientific paper. I wanted to speak more directly to the people who know this illness in deeply personal ways—patients, families, and clinicians like me. After a full professional life spent caring for and learning from these patients, I have turned to the stories themselves: their stories, their families’ stories, and, inevitably, my own.
Writing has long been important to me, and I believe it can offer a different kind of understanding—one rooted not only in science, but also in memory, compassion, and human connection.
Praise for Edges of the Mind
- Tim Shriver
- Chairman of Special Olympics and Founder of UNITE
“This book is a powerhouse of drama and science and compassion told through the eyes of a doctor on the frontlines of our nation’s struggle with serious mental illness.”
- Michael Gottlieb, MD
Physician who was the first to identify AIDS
David Pickar, M.D. dedicated his life in medicine to treating and studying patients with schizophrenia, the most disabling and misunderstood of the psychiatric illnesses. His research at Yale and the National Institute of Mental Health (NIMH ) has been foundational to our understanding of the etiology and treatment of this enigmatic brain disease. Edges of the Mind is an engaging memoir as well as a history of the remarkable progress in brain psychopharmacology that evolved over the course of his career.
- Laurie Flynn
Former Executive Director, National Alliance on Mental Illness (NAMI)